trans-Diethylstilboesterol
Brand names,
trans-Diethylstilboesterol
Analogs
trans-Diethylstilboesterol
Brand Names Mixture
trans-Diethylstilboesterol
Chemical_Formula
C22H46O
trans-Diethylstilboesterol
RX_link
No information avaliable
trans-Diethylstilboesterol
fda sheet
trans-Diethylstilboesterol
msds (material safety sheet)
trans-Diethylstilboesterol
Synthesis Reference
No information avaliable
trans-Diethylstilboesterol
Molecular Weight
326.6 g/mol
trans-Diethylstilboesterol
Melting Point
65 - 72 oC
trans-Diethylstilboesterol
H2O Solubility
No information avaliable
trans-Diethylstilboesterol
State
Solid
trans-Diethylstilboesterol
LogP
9.017
trans-Diethylstilboesterol
Dosage Forms
Topical cream (10%)
trans-Diethylstilboesterol
Indication
For the topical treatment of recurrent oral-facial herpes simplex episodes (cold sores or fever blisters).
trans-Diethylstilboesterol
Pharmacology
Docosanol is a saturated 22-carbon aliphatic alcohol which exhibits antiviral activity against many lipid enveloped viruses including herpes simplex virus (HSV). Docosanol speeds the healing of cold sores and fever blisters on the face or lips. It also relieves the accompanying symptoms, including tingling, pain, burning, and itching. Docosanol cannot, however, prevent cold sores or fever blisters from appearing.
trans-Diethylstilboesterol
Absorption
Topical absorption has been shown to be minimal under conditions reflecting normal clinical use.
trans-Diethylstilboesterol
side effects and Toxicity
Symptoms of overdose include headache, abdominal pain, increased serum lipase, nausea, dyspepsia, dizziness, and hyperbilirubinemia.
trans-Diethylstilboesterol
Patient Information
No information avaliable
trans-Diethylstilboesterol
Organisms Affected
Herpes simplex virus