Domestrol
Brand names,
Domestrol
Analogs
Domestrol
Brand Names Mixture
Domestrol
Chemical_Formula
C22H46O
Domestrol
RX_link
No information avaliable
Domestrol
fda sheet
Domestrol
msds (material safety sheet)
Domestrol
Synthesis Reference
No information avaliable
Domestrol
Molecular Weight
326.6 g/mol
Domestrol
Melting Point
65 - 72 oC
Domestrol
H2O Solubility
No information avaliable
Domestrol
State
Solid
Domestrol
LogP
9.017
Domestrol
Dosage Forms
Topical cream (10%)
Domestrol
Indication
For the topical treatment of recurrent oral-facial herpes simplex episodes (cold sores or fever blisters).
Domestrol
Pharmacology
Docosanol is a saturated 22-carbon aliphatic alcohol which exhibits antiviral activity against many lipid enveloped viruses including herpes simplex virus (HSV). Docosanol speeds the healing of cold sores and fever blisters on the face or lips. It also relieves the accompanying symptoms, including tingling, pain, burning, and itching. Docosanol cannot, however, prevent cold sores or fever blisters from appearing.
Domestrol
Absorption
Topical absorption has been shown to be minimal under conditions reflecting normal clinical use.
Domestrol
side effects and Toxicity
Symptoms of overdose include headache, abdominal pain, increased serum lipase, nausea, dyspepsia, dizziness, and hyperbilirubinemia.
Domestrol
Patient Information
No information avaliable
Domestrol
Organisms Affected
Herpes simplex virus