Comestrol estrobene
Brand names,
Comestrol estrobene
Analogs
Comestrol estrobene
Brand Names Mixture
Comestrol estrobene
Chemical_Formula
C22H46O
Comestrol estrobene
RX_link
No information avaliable
Comestrol estrobene
fda sheet
Comestrol estrobene
msds (material safety sheet)
Comestrol estrobene
Synthesis Reference
No information avaliable
Comestrol estrobene
Molecular Weight
326.6 g/mol
Comestrol estrobene
Melting Point
65 - 72 oC
Comestrol estrobene
H2O Solubility
No information avaliable
Comestrol estrobene
State
Solid
Comestrol estrobene
LogP
9.017
Comestrol estrobene
Dosage Forms
Topical cream (10%)
Comestrol estrobene
Indication
For the topical treatment of recurrent oral-facial herpes simplex episodes (cold sores or fever blisters).
Comestrol estrobene
Pharmacology
Docosanol is a saturated 22-carbon aliphatic alcohol which exhibits antiviral activity against many lipid enveloped viruses including herpes simplex virus (HSV). Docosanol speeds the healing of cold sores and fever blisters on the face or lips. It also relieves the accompanying symptoms, including tingling, pain, burning, and itching. Docosanol cannot, however, prevent cold sores or fever blisters from appearing.
Comestrol estrobene
Absorption
Topical absorption has been shown to be minimal under conditions reflecting normal clinical use.
Comestrol estrobene
side effects and Toxicity
Symptoms of overdose include headache, abdominal pain, increased serum lipase, nausea, dyspepsia, dizziness, and hyperbilirubinemia.
Comestrol estrobene
Patient Information
No information avaliable
Comestrol estrobene
Organisms Affected
Herpes simplex virus