Sedestran
Brand names,
Sedestran
Analogs
Sedestran
Brand Names Mixture
Sedestran
Chemical_Formula
C22H46O
Sedestran
RX_link
No information avaliable
Sedestran
fda sheet
Sedestran
msds (material safety sheet)
Sedestran
Synthesis Reference
No information avaliable
Sedestran
Molecular Weight
326.6 g/mol
Sedestran
Melting Point
65 - 72 oC
Sedestran
H2O Solubility
No information avaliable
Sedestran
State
Solid
Sedestran
LogP
9.017
Sedestran
Dosage Forms
Topical cream (10%)
Sedestran
Indication
For the topical treatment of recurrent oral-facial herpes simplex episodes (cold sores or fever blisters).
Sedestran
Pharmacology
Docosanol is a saturated 22-carbon aliphatic alcohol which exhibits antiviral activity against many lipid enveloped viruses including herpes simplex virus (HSV). Docosanol speeds the healing of cold sores and fever blisters on the face or lips. It also relieves the accompanying symptoms, including tingling, pain, burning, and itching. Docosanol cannot, however, prevent cold sores or fever blisters from appearing.
Sedestran
Absorption
Topical absorption has been shown to be minimal under conditions reflecting normal clinical use.
Sedestran
side effects and Toxicity
Symptoms of overdose include headache, abdominal pain, increased serum lipase, nausea, dyspepsia, dizziness, and hyperbilirubinemia.
Sedestran
Patient Information
No information avaliable
Sedestran
Organisms Affected
Herpes simplex virus