Di-Estryl
Brand names,
Di-Estryl
Analogs
Di-Estryl
Brand Names Mixture
Di-Estryl
Chemical_Formula
C22H46O
Di-Estryl
RX_link
No information avaliable
Di-Estryl
fda sheet
Di-Estryl
msds (material safety sheet)
Di-Estryl
Synthesis Reference
No information avaliable
Di-Estryl
Molecular Weight
326.6 g/mol
Di-Estryl
Melting Point
65 - 72 oC
Di-Estryl
H2O Solubility
No information avaliable
Di-Estryl
State
Solid
Di-Estryl
LogP
9.017
Di-Estryl
Dosage Forms
Topical cream (10%)
Di-Estryl
Indication
For the topical treatment of recurrent oral-facial herpes simplex episodes (cold sores or fever blisters).
Di-Estryl
Pharmacology
Docosanol is a saturated 22-carbon aliphatic alcohol which exhibits antiviral activity against many lipid enveloped viruses including herpes simplex virus (HSV). Docosanol speeds the healing of cold sores and fever blisters on the face or lips. It also relieves the accompanying symptoms, including tingling, pain, burning, and itching. Docosanol cannot, however, prevent cold sores or fever blisters from appearing.
Di-Estryl
Absorption
Topical absorption has been shown to be minimal under conditions reflecting normal clinical use.
Di-Estryl
side effects and Toxicity
Symptoms of overdose include headache, abdominal pain, increased serum lipase, nausea, dyspepsia, dizziness, and hyperbilirubinemia.
Di-Estryl
Patient Information
No information avaliable
Di-Estryl
Organisms Affected
Herpes simplex virus