Grafestrol
Brand names,
Grafestrol
Analogs
Grafestrol
Brand Names Mixture
Grafestrol
Chemical_Formula
C22H46O
Grafestrol
RX_link
No information avaliable
Grafestrol
fda sheet
Grafestrol
msds (material safety sheet)
Grafestrol
Synthesis Reference
No information avaliable
Grafestrol
Molecular Weight
326.6 g/mol
Grafestrol
Melting Point
65 - 72 oC
Grafestrol
H2O Solubility
No information avaliable
Grafestrol
State
Solid
Grafestrol
LogP
9.017
Grafestrol
Dosage Forms
Topical cream (10%)
Grafestrol
Indication
For the topical treatment of recurrent oral-facial herpes simplex episodes (cold sores or fever blisters).
Grafestrol
Pharmacology
Docosanol is a saturated 22-carbon aliphatic alcohol which exhibits antiviral activity against many lipid enveloped viruses including herpes simplex virus (HSV). Docosanol speeds the healing of cold sores and fever blisters on the face or lips. It also relieves the accompanying symptoms, including tingling, pain, burning, and itching. Docosanol cannot, however, prevent cold sores or fever blisters from appearing.
Grafestrol
Absorption
Topical absorption has been shown to be minimal under conditions reflecting normal clinical use.
Grafestrol
side effects and Toxicity
Symptoms of overdose include headache, abdominal pain, increased serum lipase, nausea, dyspepsia, dizziness, and hyperbilirubinemia.
Grafestrol
Patient Information
No information avaliable
Grafestrol
Organisms Affected
Herpes simplex virus