Sibol
Brand names,
Sibol
Analogs
Sibol
Brand Names Mixture
Sibol
Chemical_Formula
C22H46O
Sibol
RX_link
No information avaliable
Sibol
fda sheet
Sibol
msds (material safety sheet)
Sibol
Synthesis Reference
No information avaliable
Sibol
Molecular Weight
326.6 g/mol
Sibol
Melting Point
65 - 72 oC
Sibol
H2O Solubility
No information avaliable
Sibol
State
Solid
Sibol
LogP
9.017
Sibol
Dosage Forms
Topical cream (10%)
Sibol
Indication
For the topical treatment of recurrent oral-facial herpes simplex episodes (cold sores or fever blisters).
Sibol
Pharmacology
Docosanol is a saturated 22-carbon aliphatic alcohol which exhibits antiviral activity against many lipid enveloped viruses including herpes simplex virus (HSV). Docosanol speeds the healing of cold sores and fever blisters on the face or lips. It also relieves the accompanying symptoms, including tingling, pain, burning, and itching. Docosanol cannot, however, prevent cold sores or fever blisters from appearing.
Sibol
Absorption
Topical absorption has been shown to be minimal under conditions reflecting normal clinical use.
Sibol
side effects and Toxicity
Symptoms of overdose include headache, abdominal pain, increased serum lipase, nausea, dyspepsia, dizziness, and hyperbilirubinemia.
Sibol
Patient Information
No information avaliable
Sibol
Organisms Affected
Herpes simplex virus