Climaterine
Brand names,
Climaterine
Analogs
Climaterine
Brand Names Mixture
Climaterine
Chemical_Formula
C22H46O
Climaterine
RX_link
No information avaliable
Climaterine
fda sheet
Climaterine
msds (material safety sheet)
Climaterine
Synthesis Reference
No information avaliable
Climaterine
Molecular Weight
326.6 g/mol
Climaterine
Melting Point
65 - 72 oC
Climaterine
H2O Solubility
No information avaliable
Climaterine
State
Solid
Climaterine
LogP
9.017
Climaterine
Dosage Forms
Topical cream (10%)
Climaterine
Indication
For the topical treatment of recurrent oral-facial herpes simplex episodes (cold sores or fever blisters).
Climaterine
Pharmacology
Docosanol is a saturated 22-carbon aliphatic alcohol which exhibits antiviral activity against many lipid enveloped viruses including herpes simplex virus (HSV). Docosanol speeds the healing of cold sores and fever blisters on the face or lips. It also relieves the accompanying symptoms, including tingling, pain, burning, and itching. Docosanol cannot, however, prevent cold sores or fever blisters from appearing.
Climaterine
Absorption
Topical absorption has been shown to be minimal under conditions reflecting normal clinical use.
Climaterine
side effects and Toxicity
Symptoms of overdose include headache, abdominal pain, increased serum lipase, nausea, dyspepsia, dizziness, and hyperbilirubinemia.
Climaterine
Patient Information
No information avaliable
Climaterine
Organisms Affected
Herpes simplex virus