Comestrol
Brand names,
Comestrol
Analogs
Comestrol
Brand Names Mixture
Comestrol
Chemical_Formula
C22H46O
Comestrol
RX_link
No information avaliable
Comestrol
fda sheet
Comestrol
msds (material safety sheet)
Comestrol
Synthesis Reference
No information avaliable
Comestrol
Molecular Weight
326.6 g/mol
Comestrol
Melting Point
65 - 72 oC
Comestrol
H2O Solubility
No information avaliable
Comestrol
State
Solid
Comestrol
LogP
9.017
Comestrol
Dosage Forms
Topical cream (10%)
Comestrol
Indication
For the topical treatment of recurrent oral-facial herpes simplex episodes (cold sores or fever blisters).
Comestrol
Pharmacology
Docosanol is a saturated 22-carbon aliphatic alcohol which exhibits antiviral activity against many lipid enveloped viruses including herpes simplex virus (HSV). Docosanol speeds the healing of cold sores and fever blisters on the face or lips. It also relieves the accompanying symptoms, including tingling, pain, burning, and itching. Docosanol cannot, however, prevent cold sores or fever blisters from appearing.
Comestrol
Absorption
Topical absorption has been shown to be minimal under conditions reflecting normal clinical use.
Comestrol
side effects and Toxicity
Symptoms of overdose include headache, abdominal pain, increased serum lipase, nausea, dyspepsia, dizziness, and hyperbilirubinemia.
Comestrol
Patient Information
No information avaliable
Comestrol
Organisms Affected
Herpes simplex virus