Makarol
Brand names,
Makarol
Analogs
Makarol
Brand Names Mixture
Makarol
Chemical_Formula
C22H46O
Makarol
RX_link
No information avaliable
Makarol
fda sheet
Makarol
msds (material safety sheet)
Makarol
Synthesis Reference
No information avaliable
Makarol
Molecular Weight
326.6 g/mol
Makarol
Melting Point
65 - 72 oC
Makarol
H2O Solubility
No information avaliable
Makarol
State
Solid
Makarol
LogP
9.017
Makarol
Dosage Forms
Topical cream (10%)
Makarol
Indication
For the topical treatment of recurrent oral-facial herpes simplex episodes (cold sores or fever blisters).
Makarol
Pharmacology
Docosanol is a saturated 22-carbon aliphatic alcohol which exhibits antiviral activity against many lipid enveloped viruses including herpes simplex virus (HSV). Docosanol speeds the healing of cold sores and fever blisters on the face or lips. It also relieves the accompanying symptoms, including tingling, pain, burning, and itching. Docosanol cannot, however, prevent cold sores or fever blisters from appearing.
Makarol
Absorption
Topical absorption has been shown to be minimal under conditions reflecting normal clinical use.
Makarol
side effects and Toxicity
Symptoms of overdose include headache, abdominal pain, increased serum lipase, nausea, dyspepsia, dizziness, and hyperbilirubinemia.
Makarol
Patient Information
No information avaliable
Makarol
Organisms Affected
Herpes simplex virus