Estrobene
Brand names,
Estrobene
Analogs
Estrobene
Brand Names Mixture
Estrobene
Chemical_Formula
C22H46O
Estrobene
RX_link
No information avaliable
Estrobene
fda sheet
Estrobene
msds (material safety sheet)
Estrobene
Synthesis Reference
No information avaliable
Estrobene
Molecular Weight
326.6 g/mol
Estrobene
Melting Point
65 - 72 oC
Estrobene
H2O Solubility
No information avaliable
Estrobene
State
Solid
Estrobene
LogP
9.017
Estrobene
Dosage Forms
Topical cream (10%)
Estrobene
Indication
For the topical treatment of recurrent oral-facial herpes simplex episodes (cold sores or fever blisters).
Estrobene
Pharmacology
Docosanol is a saturated 22-carbon aliphatic alcohol which exhibits antiviral activity against many lipid enveloped viruses including herpes simplex virus (HSV). Docosanol speeds the healing of cold sores and fever blisters on the face or lips. It also relieves the accompanying symptoms, including tingling, pain, burning, and itching. Docosanol cannot, however, prevent cold sores or fever blisters from appearing.
Estrobene
Absorption
Topical absorption has been shown to be minimal under conditions reflecting normal clinical use.
Estrobene
side effects and Toxicity
Symptoms of overdose include headache, abdominal pain, increased serum lipase, nausea, dyspepsia, dizziness, and hyperbilirubinemia.
Estrobene
Patient Information
No information avaliable
Estrobene
Organisms Affected
Herpes simplex virus