Agostilben
Brand names,
Agostilben
Analogs
Agostilben
Brand Names Mixture
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Chemical_Formula
C22H46O
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RX_link
No information avaliable
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
326.6 g/mol
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Melting Point
65 - 72 oC
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H2O Solubility
No information avaliable
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State
Solid
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LogP
9.017
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Dosage Forms
Topical cream (10%)
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Indication
For the topical treatment of recurrent oral-facial herpes simplex episodes (cold sores or fever blisters).
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Pharmacology
Docosanol is a saturated 22-carbon aliphatic alcohol which exhibits antiviral activity against many lipid enveloped viruses including herpes simplex virus (HSV). Docosanol speeds the healing of cold sores and fever blisters on the face or lips. It also relieves the accompanying symptoms, including tingling, pain, burning, and itching. Docosanol cannot, however, prevent cold sores or fever blisters from appearing.
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Absorption
Topical absorption has been shown to be minimal under conditions reflecting normal clinical use.
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side effects and Toxicity
Symptoms of overdose include headache, abdominal pain, increased serum lipase, nausea, dyspepsia, dizziness, and hyperbilirubinemia.
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Patient Information
No information avaliable
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Organisms Affected
Herpes simplex virus