n-Nonanedioic acid en es it fr

n-Nonanedioic acid Brand names, n-Nonanedioic acid Analogs

n-Nonanedioic acid Brand Names Mixture

  • No information avaliable

n-Nonanedioic acid Chemical_Formula

C9H16O4

n-Nonanedioic acid RX_link

http://www.rxlist.com/cgi/generic3/azelex.htm

n-Nonanedioic acid fda sheet

n-Nonanedioic_acid FDA

n-Nonanedioic acid msds (material safety sheet)

n-Nonanedioic_acid MSDS

n-Nonanedioic acid Synthesis Reference

No information avaliable

n-Nonanedioic acid Molecular Weight

188.221 g/mol

n-Nonanedioic acid Melting Point

106.5 oC

n-Nonanedioic acid H2O Solubility

2400 mg/L (20°C)

n-Nonanedioic acid State

Solid

n-Nonanedioic acid LogP

1.646

n-Nonanedioic acid Dosage Forms

Cream (20%)

n-Nonanedioic acid Indication

For the topical treatment of mild-to-moderate inflammatory acne vulgaris.

n-Nonanedioic acid Pharmacology

Azelaic acid is a saturated dicarboxylic acid found naturally in wheat, rye, and barley. It is a natural substance that is produced by Malassezia furfur (also known as Pityrosporum ovale), a yeast that lives on normal skin. It is effective against a number of skin conditions, such as mild to moderate acne, when applied topically in a cream formulation of 20%. It works in part by stopping the growth of skin bacteria that cause acne, and by keeping skin pores clear. Azelaic acid's antimicrobial action may be attributable to inhibition of microbial cellular protein synthesis.

n-Nonanedioic acid Absorption

Approximately 4% of the topically applied azelaic acid is systemically absorbed.

n-Nonanedioic acid side effects and Toxicity

Oral, rat: LD50 = >5 gm/kg.

n-Nonanedioic acid Patient Information

n-Nonanedioic acid Organisms Affected

Various aerobic and anaerobic microorganisms