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Lepargylic acid Brand names, Lepargylic acid Analogs

Lepargylic acid Brand Names Mixture

  • No information avaliable

Lepargylic acid Chemical_Formula

C9H16O4

Lepargylic acid RX_link

http://www.rxlist.com/cgi/generic3/azelex.htm

Lepargylic acid fda sheet

Lepargylic_acid FDA

Lepargylic acid msds (material safety sheet)

Lepargylic_acid MSDS

Lepargylic acid Synthesis Reference

No information avaliable

Lepargylic acid Molecular Weight

188.221 g/mol

Lepargylic acid Melting Point

106.5 oC

Lepargylic acid H2O Solubility

2400 mg/L (20°C)

Lepargylic acid State

Solid

Lepargylic acid LogP

1.646

Lepargylic acid Dosage Forms

Cream (20%)

Lepargylic acid Indication

For the topical treatment of mild-to-moderate inflammatory acne vulgaris.

Lepargylic acid Pharmacology

Azelaic acid is a saturated dicarboxylic acid found naturally in wheat, rye, and barley. It is a natural substance that is produced by Malassezia furfur (also known as Pityrosporum ovale), a yeast that lives on normal skin. It is effective against a number of skin conditions, such as mild to moderate acne, when applied topically in a cream formulation of 20%. It works in part by stopping the growth of skin bacteria that cause acne, and by keeping skin pores clear. Azelaic acid's antimicrobial action may be attributable to inhibition of microbial cellular protein synthesis.

Lepargylic acid Absorption

Approximately 4% of the topically applied azelaic acid is systemically absorbed.

Lepargylic acid side effects and Toxicity

Oral, rat: LD50 = >5 gm/kg.

Lepargylic acid Patient Information

Lepargylic acid Organisms Affected

Various aerobic and anaerobic microorganisms