Heptanedicarboxylic acid
Heptanedicarboxylic acid Brand names, Heptanedicarboxylic acid Analogs
Heptanedicarboxylic acid Brand Names Mixture
- No information avaliable
Heptanedicarboxylic acid Chemical_Formula
C9H16O4
Heptanedicarboxylic acid RX_link
http://www.rxlist.com/cgi/generic3/azelex.htm
Heptanedicarboxylic acid fda sheet
Heptanedicarboxylic acid msds (material safety sheet)
Heptanedicarboxylic acid Synthesis Reference
No information avaliable
Heptanedicarboxylic acid Molecular Weight
188.221 g/mol
Heptanedicarboxylic acid Melting Point
106.5 oC
Heptanedicarboxylic acid H2O Solubility
2400 mg/L (20°C)
Heptanedicarboxylic acid State
Solid
Heptanedicarboxylic acid LogP
1.646
Heptanedicarboxylic acid Dosage Forms
Cream (20%)
Heptanedicarboxylic acid Indication
For the topical treatment of mild-to-moderate inflammatory acne vulgaris.
Heptanedicarboxylic acid Pharmacology
Azelaic acid is a saturated dicarboxylic acid found naturally in wheat, rye, and barley. It is a natural substance that is produced by Malassezia furfur (also known as Pityrosporum ovale), a yeast that lives on normal skin. It is effective against a number of skin conditions, such as mild to moderate acne, when applied topically in a cream formulation of 20%. It works in part by stopping the growth of skin bacteria that cause acne, and by keeping skin pores clear. Azelaic acid's antimicrobial action may be attributable to inhibition of microbial cellular protein synthesis.
Heptanedicarboxylic acid Absorption
Approximately 4% of the topically applied azelaic acid is systemically absorbed.
Heptanedicarboxylic acid side effects and Toxicity
Oral, rat: LD50 = >5 gm/kg.
Heptanedicarboxylic acid Patient Information
Heptanedicarboxylic acid Organisms Affected
Various aerobic and anaerobic microorganisms
