Finacea
Finacea Brand names, Finacea Analogs
Finacea Brand Names Mixture
- No information avaliable
Finacea Chemical_Formula
C9H16O4
Finacea RX_link
http://www.rxlist.com/cgi/generic3/azelex.htm
Finacea fda sheet
Finacea msds (material safety sheet)
Finacea Synthesis Reference
No information avaliable
Finacea Molecular Weight
188.221 g/mol
Finacea Melting Point
106.5 oC
Finacea H2O Solubility
2400 mg/L (20°C)
Finacea State
Solid
Finacea LogP
1.646
Finacea Dosage Forms
Cream (20%)
Finacea Indication
For the topical treatment of mild-to-moderate inflammatory acne vulgaris.
Finacea Pharmacology
Azelaic acid is a saturated dicarboxylic acid found naturally in wheat, rye, and barley. It is a natural substance that is produced by Malassezia furfur (also known as Pityrosporum ovale), a yeast that lives on normal skin. It is effective against a number of skin conditions, such as mild to moderate acne, when applied topically in a cream formulation of 20%. It works in part by stopping the growth of skin bacteria that cause acne, and by keeping skin pores clear. Azelaic acid's antimicrobial action may be attributable to inhibition of microbial cellular protein synthesis.
Finacea Absorption
Approximately 4% of the topically applied azelaic acid is systemically absorbed.
Finacea side effects and Toxicity
Oral, rat: LD50 = >5 gm/kg.
Finacea Patient Information
Finacea Organisms Affected
Various aerobic and anaerobic microorganisms
