Azelaicacidtech
Azelaicacidtech Brand names, Azelaicacidtech Analogs
Azelaicacidtech Brand Names Mixture
- No information avaliable
Azelaicacidtech Chemical_Formula
C9H16O4
Azelaicacidtech RX_link
http://www.rxlist.com/cgi/generic3/azelex.htm
Azelaicacidtech fda sheet
Azelaicacidtech msds (material safety sheet)
Azelaicacidtech Synthesis Reference
No information avaliable
Azelaicacidtech Molecular Weight
188.221 g/mol
Azelaicacidtech Melting Point
106.5 oC
Azelaicacidtech H2O Solubility
2400 mg/L (20°C)
Azelaicacidtech State
Solid
Azelaicacidtech LogP
1.646
Azelaicacidtech Dosage Forms
Cream (20%)
Azelaicacidtech Indication
For the topical treatment of mild-to-moderate inflammatory acne vulgaris.
Azelaicacidtech Pharmacology
Azelaic acid is a saturated dicarboxylic acid found naturally in wheat, rye, and barley. It is a natural substance that is produced by Malassezia furfur (also known as Pityrosporum ovale), a yeast that lives on normal skin. It is effective against a number of skin conditions, such as mild to moderate acne, when applied topically in a cream formulation of 20%. It works in part by stopping the growth of skin bacteria that cause acne, and by keeping skin pores clear. Azelaic acid's antimicrobial action may be attributable to inhibition of microbial cellular protein synthesis.
Azelaicacidtech Absorption
Approximately 4% of the topically applied azelaic acid is systemically absorbed.
Azelaicacidtech side effects and Toxicity
Oral, rat: LD50 = >5 gm/kg.
Azelaicacidtech Patient Information
Azelaicacidtech Organisms Affected
Various aerobic and anaerobic microorganisms
