Azelaic acid, technical grade
Azelaic acid, technical grade Brand names, Azelaic acid, technical grade Analogs
Azelaic acid, technical grade Brand Names Mixture
- No information avaliable
Azelaic acid, technical grade Chemical_Formula
C9H16O4
Azelaic acid, technical grade RX_link
http://www.rxlist.com/cgi/generic3/azelex.htm
Azelaic acid, technical grade fda sheet
Azelaic acid, technical grade msds (material safety sheet)
Azelaic acid, technical grade Synthesis Reference
No information avaliable
Azelaic acid, technical grade Molecular Weight
188.221 g/mol
Azelaic acid, technical grade Melting Point
106.5 oC
Azelaic acid, technical grade H2O Solubility
2400 mg/L (20°C)
Azelaic acid, technical grade State
Solid
Azelaic acid, technical grade LogP
1.646
Azelaic acid, technical grade Dosage Forms
Cream (20%)
Azelaic acid, technical grade Indication
For the topical treatment of mild-to-moderate inflammatory acne vulgaris.
Azelaic acid, technical grade Pharmacology
Azelaic acid is a saturated dicarboxylic acid found naturally in wheat, rye, and barley. It is a natural substance that is produced by Malassezia furfur (also known as Pityrosporum ovale), a yeast that lives on normal skin. It is effective against a number of skin conditions, such as mild to moderate acne, when applied topically in a cream formulation of 20%. It works in part by stopping the growth of skin bacteria that cause acne, and by keeping skin pores clear. Azelaic acid's antimicrobial action may be attributable to inhibition of microbial cellular protein synthesis.
Azelaic acid, technical grade Absorption
Approximately 4% of the topically applied azelaic acid is systemically absorbed.
Azelaic acid, technical grade side effects and Toxicity
Oral, rat: LD50 = >5 gm/kg.
Azelaic acid, technical grade Patient Information
Azelaic acid, technical grade Organisms Affected
Various aerobic and anaerobic microorganisms
