Finevin
Finevin Brand names, Finevin Analogs
Finevin Brand Names Mixture
- No information avaliable
Finevin Chemical_Formula
C9H16O4
Finevin RX_link
http://www.rxlist.com/cgi/generic3/azelex.htm
Finevin fda sheet
Finevin msds (material safety sheet)
Finevin Synthesis Reference
No information avaliable
Finevin Molecular Weight
188.221 g/mol
Finevin Melting Point
106.5 oC
Finevin H2O Solubility
2400 mg/L (20°C)
Finevin State
Solid
Finevin LogP
1.646
Finevin Dosage Forms
Cream (20%)
Finevin Indication
For the topical treatment of mild-to-moderate inflammatory acne vulgaris.
Finevin Pharmacology
Azelaic acid is a saturated dicarboxylic acid found naturally in wheat, rye, and barley. It is a natural substance that is produced by Malassezia furfur (also known as Pityrosporum ovale), a yeast that lives on normal skin. It is effective against a number of skin conditions, such as mild to moderate acne, when applied topically in a cream formulation of 20%. It works in part by stopping the growth of skin bacteria that cause acne, and by keeping skin pores clear. Azelaic acid's antimicrobial action may be attributable to inhibition of microbial cellular protein synthesis.
Finevin Absorption
Approximately 4% of the topically applied azelaic acid is systemically absorbed.
Finevin side effects and Toxicity
Oral, rat: LD50 = >5 gm/kg.
Finevin Patient Information
Finevin Organisms Affected
Various aerobic and anaerobic microorganisms
