Emerox 1144
Emerox 1144 Brand names, Emerox 1144 Analogs
Emerox 1144 Brand Names Mixture
- No information avaliable
Emerox 1144 Chemical_Formula
C9H16O4
Emerox 1144 RX_link
http://www.rxlist.com/cgi/generic3/azelex.htm
Emerox 1144 fda sheet
Emerox 1144 msds (material safety sheet)
Emerox 1144 Synthesis Reference
No information avaliable
Emerox 1144 Molecular Weight
188.221 g/mol
Emerox 1144 Melting Point
106.5 oC
Emerox 1144 H2O Solubility
2400 mg/L (20°C)
Emerox 1144 State
Solid
Emerox 1144 LogP
1.646
Emerox 1144 Dosage Forms
Cream (20%)
Emerox 1144 Indication
For the topical treatment of mild-to-moderate inflammatory acne vulgaris.
Emerox 1144 Pharmacology
Azelaic acid is a saturated dicarboxylic acid found naturally in wheat, rye, and barley. It is a natural substance that is produced by Malassezia furfur (also known as Pityrosporum ovale), a yeast that lives on normal skin. It is effective against a number of skin conditions, such as mild to moderate acne, when applied topically in a cream formulation of 20%. It works in part by stopping the growth of skin bacteria that cause acne, and by keeping skin pores clear. Azelaic acid's antimicrobial action may be attributable to inhibition of microbial cellular protein synthesis.
Emerox 1144 Absorption
Approximately 4% of the topically applied azelaic acid is systemically absorbed.
Emerox 1144 side effects and Toxicity
Oral, rat: LD50 = >5 gm/kg.
Emerox 1144 Patient Information
Emerox 1144 Organisms Affected
Various aerobic and anaerobic microorganisms
