Dimethylbenzimidazoylcobamide

Categoria

Dimethylbenzimidazoylcobamide Nombres de marca, Dimethylbenzimidazoylcobamide Analogos

Dimethylbenzimidazoylcobamide Marca los nombres de mezcla

Liver-Stomach Concentrate with Intrinsic Factor (Special Liver-Stomach Concentrate + Vitamin B 12 + Iron + Ascorbic Acid + Folic Acid)

Dimethylbenzimidazoylcobamide Formula quimica

C₆₃H₈₈CoN₁₄O₁₄P

Dimethylbenzimidazoylcobamide RX enlace

http://www.rxlist.com/cgi/generic2/hminfr.htm

Dimethylbenzimidazoylcobamide FDA hoja

Dimethylbenzimidazoylcobamide MSDS (hoja de seguridad de materiales)

Dimethylbenzimidazoylcobamide MSDS

Dimethylbenzimidazoylcobamide Sintesis de referencia

No hay información disponible

Dimethylbenzimidazoylcobamide Peso molecular

1355.37 g/mol

Dimethylbenzimidazoylcobamide Punto de fusion

> 300 ^oC

Dimethylbenzimidazoylcobamide H₂O Solubilidad

1.25E 004 mg / L

Dimethylbenzimidazoylcobamide Estado

Solid

Dimethylbenzimidazoylcobamide LogP

3.57

Dimethylbenzimidazoylcobamide Formas de dosificacion

Intranasal gel; parenteral (oral)

Dimethylbenzimidazoylcobamide Indicacion

Para el tratamiento de la anemia perniciosa (debida a la falta o la inhibición del factor intrínseco) y para la prevención y tratamiento de la deficiencia de vitamina B12.

Dimethylbenzimidazoylcobamide Farmacologia

La vitamina B12 es un compuesto organometálico soluble en agua con un ion cobalto trivalente atado dentro de un anillo de corrina. Se isneeded para las células nerviosas y los glóbulos rojos, y para hacer el ADN. Deficiencia de vitamina B12 es la causa de varias formas de anemia.

Dimethylbenzimidazoylcobamide Absorcion

Se absorbe rápidamente en la mitad inferior del íleon.

Dimethylbenzimidazoylcobamide Toxicidad

Reacción anafiláctica (erupciones en la piel, picazón, dificultad para respirar) después de la administración parenteral. ORL-MUS LD50> 8000 mg / kg

Dimethylbenzimidazoylcobamide Informacion de Pacientes

Patients with pernicious anemia should be informed that they will require monthly injections of vitamin B12 for the remainder of their lives. Failure to do so will result in return of the anemia and in development of incapacitating and irreversible damage to the nerves of the spinal cord. Also, patients should be warned about the danger of taking folic acid in place of vitamin B12, because the former may prevent anemia but allow progression of subacute combined degeneration. A vegetarian diet which contains no animal products (including milk products or eggs) does not supply any vitamin B12. Patients following such a diet, should be advised to take oral vitamin B12 regularly. The need for vitamin B12 is increased by pregnancy and lactation. Deficiency has been recognized in infants of vegetarian mothers who were breast fed, even though the mothers had no symptoms of deficiency at the time.

Dimethylbenzimidazoylcobamide Organismos afectados

Humanos y otros mamíferos