Bevidox Concentrate
Brand names,
Bevidox Concentrate
Analogs
Bevidox Concentrate
Brand Names Mixture
- Liver-Stomach Concentrate with Intrinsic Factor (Special Liver-Stomach Concentrate + Vitamin B 12 + Iron + Ascorbic Acid + Folic Acid)
Bevidox Concentrate
Chemical_Formula
C63H88CoN14O14P
Bevidox Concentrate
RX_link
http://www.rxlist.com/cgi/generic2/hminfr.htm
Bevidox Concentrate
fda sheet
Bevidox Concentrate
msds (material safety sheet)
Bevidox Concentrate
Synthesis Reference
No information avaliable
Bevidox Concentrate
Molecular Weight
1355.37 g/mol
Bevidox Concentrate
Melting Point
> 300 oC
Bevidox Concentrate
H2O Solubility
1.25E+004 mg/L
Bevidox Concentrate
State
Solid
Bevidox Concentrate
LogP
3.57
Bevidox Concentrate
Dosage Forms
Intra-nasal gel; Parenteral (oral)
Bevidox Concentrate
Indication
For treatment of pernicious anemia (due to lack of or inhibition of intrinsic factor) and for prevention and treatment of vitamin B 12 deficiency.
Bevidox Concentrate
Pharmacology
Vitamin B12 is a water-soluble organometallic compound with a trivalent cobalt ion bound inside a corrin ring. It isneeded for nerve cells and red blood cells, and to make DNA. Vitamin B12 deficiency is the cause of several forms of anemia.
Bevidox Concentrate
Absorption
Readily absorbed in the lower half of the ileum.
Bevidox Concentrate
side effects and Toxicity
Anaphylactic reaction (skin rash, itching, wheezing)-after parenteral administration. ORL-MUS LD50 > 8000 mg/kg
Bevidox Concentrate
Patient Information
Patients with pernicious anemia should be informed that they will require monthly injections of vitamin B12 for the remainder of their lives. Failure to do so will result in return of the anemia and in development of incapacitating and irreversible damage to the nerves of the spinal cord. Also, patients should be warned about the danger of taking folic acid in place of vitamin B12, because the former may prevent anemia but allow progression of subacute combined degeneration. A vegetarian diet which contains no animal products (including milk products or eggs) does not supply any vitamin B12. Patients following such a diet, should be advised to take oral vitamin B12 regularly. The need for vitamin B12 is increased by pregnancy and lactation. Deficiency has been recognized in infants of vegetarian mothers who were breast fed, even though the mothers had no symptoms of deficiency at the time.
Bevidox Concentrate
Organisms Affected
Humans and other mammals