Cobalin
Cobalin Brand names, Cobalin Analogs
- Anacobin
- B-Twelve
- B-Twelve Ora
- Berubigen
- Betalin 12, Crystalline
- Betalin-12
- Betaline-12
- Betolvex
- Bevatine-12
- Bevidox
- Bevidox Concentrate
- Biocobalamine
- Byladoce
- CN-B12
- Cabadon M
- Cobadoce Forte
- Cobalamin
- Cobalamin Concentrate
- Cobalamin, Cyanide
- Cobalamin, Cyano-
- Cobalin
- Cobamin
- Cobavite
- Cobione
- Coobalamed
- Copharvit 5000
- Cosmo-Rey
- Cotel
- Covit
- Crystamin
- Crystamine
- Crystimin
- Crystwel
- Cyano-B12
- Cyanobalamin Concentrate
- Cyanocobalamin Vitamin B12
- Cyanocobalamine
- Cyanocobalmin
- Cycobemin
- Cycolamin
- Cykobemin
- Cykobeminet
- Cynobal
- Cyomin
- Cyredin
- Cytacon
- Cytamen
- Cytobion
- Depinar
- Dicopac
- Dimethylbenzimidazoylcobamide
- Distivit
- Dobetin
- Docemine
- Docibin
- Docigram
- Docivit
- Dodecabee
- Dodecavite
- Dodex
- Ducobee
- Duodecibin
- Embiol
- Emociclina
- Eritrone
- Erycytol
- Erythrotin
- Euhaemon
- Extrinsic Factor
- Factor II
- Fermin
- Fresmin
- Hemomin
- Hepagon
- Hepavis
- Hepcovite
- Hylugel Plus
- Lactobacillus Lactis Dorner Factor
- Lld Factor
- Macrabin
- Megabion
- Megalovel
- Milbedoce
- Millevit
- Nagravon
- Normocytin
- Novidroxin
- Pernaemon
- Pernaevit
- Pernipuron
- Plecyamin
- Poyamin
- Rebramin
- Redamina
- Redisol
- Rhodacryst
- Rubesol
- Rubramin
- Rubramin Pc
- Rubripca
- Rubrocitol
- Sytobex
- Vi-Twel
- Vibalt
- Vibisone
- Virubra
- Vita-Rubra
- Vitamin B12 BP
- Vitamin B12 Complex
- Vitamin B12 Preparation
- Vitamin B12b
- Vitamine B12
- Vitarubin
- Vitral
Cobalin Brand Names Mixture
- Liver-Stomach Concentrate with Intrinsic Factor (Special Liver-Stomach Concentrate + Vitamin B 12 + Iron + Ascorbic Acid + Folic Acid)
Cobalin Chemical_Formula
C63H88CoN14O14P
Cobalin RX_link
http://www.rxlist.com/cgi/generic2/hminfr.htm
Cobalin fda sheet
Cobalin msds (material safety sheet)
Cobalin Synthesis Reference
No information avaliable
Cobalin Molecular Weight
1355.37 g/mol
Cobalin Melting Point
> 300 oC
Cobalin H2O Solubility
1.25E+004 mg/L
Cobalin State
Solid
Cobalin LogP
3.57
Cobalin Dosage Forms
Intra-nasal gel; Parenteral (oral)
Cobalin Indication
For treatment of pernicious anemia (due to lack of or inhibition of intrinsic factor) and for prevention and treatment of vitamin B 12 deficiency.
Cobalin Pharmacology
Vitamin B12 is a water-soluble organometallic compound with a trivalent cobalt ion bound inside a corrin ring. It isneeded for nerve cells and red blood cells, and to make DNA. Vitamin B12 deficiency is the cause of several forms of anemia.
Cobalin Absorption
Readily absorbed in the lower half of the ileum.
Cobalin side effects and Toxicity
Anaphylactic reaction (skin rash, itching, wheezing)-after parenteral administration. ORL-MUS LD50 > 8000 mg/kg
Cobalin Patient Information
Patients with pernicious anemia should be informed that they will require monthly injections of vitamin B12 for the remainder of their lives. Failure to do so will result in return of the anemia and in development of incapacitating and irreversible damage to the nerves of the spinal cord. Also, patients should be warned about the danger of taking folic acid in place of vitamin B12, because the former may prevent anemia but allow progression of subacute combined degeneration. A vegetarian diet which contains no animal products (including milk products or eggs) does not supply any vitamin B12. Patients following such a diet, should be advised to take oral vitamin B12 regularly. The need for vitamin B12 is increased by pregnancy and lactation. Deficiency has been recognized in infants of vegetarian mothers who were breast fed, even though the mothers had no symptoms of deficiency at the time.
Cobalin Organisms Affected
Humans and other mammals
