Temesta
Brand names,
Temesta
Analogs
Temesta
Brand Names Mixture
Temesta
Chemical_Formula
C15H10Cl2N2O2
Temesta
RX_link
http://www.rxlist.com/cgi/generic/loraz.htm
Temesta
fda sheet
Temesta
msds (material safety sheet)
Temesta
Synthesis Reference
Childress, Gluckman, J. Pharm. Sci. 53, 577 (1964)
Temesta
Molecular Weight
321.158 g/mol
Temesta
Melting Point
166-168oC
Temesta
H2O Solubility
0.08 mg/mL
Temesta
State
Solid
Temesta
LogP
2.959
Temesta
Dosage Forms
Tablet; Injection
Temesta
Indication
For the management of anxiety disorders or for the short-term relief of the symptoms of anxiety or anxiety associated with depressive symptoms
Temesta
Pharmacology
Lorazepam, a benzodiazepine not transformed to active metabolites, is used to treat anxiety, status epilepticus, and for sedation induction and anterograde amnesia.
Temesta
Absorption
Readily absorbed with an absolute bioavailability of 90%.
Temesta
side effects and Toxicity
Somnolence, confusion, and coma, LD50=3178mg/kg (orally in mice).
Temesta
Patient Information
Lorazepam is a benzodiazepine used for the treatment of anxiety, anxiety with depression, and insomnia. Inform
your physician if you are pregnant or nursing. Lorazepam may cause dizziness and drowsiness; use caution while
driving or operating hazardous machinery. Do not take any other sedating drugs or drink alcohol while taking this
medication. Lorazepam may be habit forming. It is advisable that patients consult with their physician before
changing the dose. Withdrawal symptoms may occur after you stop taking it. This medication may be taken with or
without food.
Temesta
Organisms Affected
Humans and other mammals