Almazine
Brand names,
Almazine
Analogs
Almazine
Brand Names Mixture
Almazine
Chemical_Formula
C15H10Cl2N2O2
Almazine
RX_link
http://www.rxlist.com/cgi/generic/loraz.htm
Almazine
fda sheet
Almazine
msds (material safety sheet)
Almazine
Synthesis Reference
Childress, Gluckman, J. Pharm. Sci. 53, 577 (1964)
Almazine
Molecular Weight
321.158 g/mol
Almazine
Melting Point
166-168oC
Almazine
H2O Solubility
0.08 mg/mL
Almazine
State
Solid
Almazine
LogP
2.959
Almazine
Dosage Forms
Tablet; Injection
Almazine
Indication
For the management of anxiety disorders or for the short-term relief of the symptoms of anxiety or anxiety associated with depressive symptoms
Almazine
Pharmacology
Lorazepam, a benzodiazepine not transformed to active metabolites, is used to treat anxiety, status epilepticus, and for sedation induction and anterograde amnesia.
Almazine
Absorption
Readily absorbed with an absolute bioavailability of 90%.
Almazine
side effects and Toxicity
Somnolence, confusion, and coma, LD50=3178mg/kg (orally in mice).
Almazine
Patient Information
Lorazepam is a benzodiazepine used for the treatment of anxiety, anxiety with depression, and insomnia. Inform
your physician if you are pregnant or nursing. Lorazepam may cause dizziness and drowsiness; use caution while
driving or operating hazardous machinery. Do not take any other sedating drugs or drink alcohol while taking this
medication. Lorazepam may be habit forming. It is advisable that patients consult with their physician before
changing the dose. Withdrawal symptoms may occur after you stop taking it. This medication may be taken with or
without food.
Almazine
Organisms Affected
Humans and other mammals