Ativan
Brand names,
Ativan
Analogs
Ativan
Brand Names Mixture
Ativan
Chemical_Formula
C15H10Cl2N2O2
Ativan
RX_link
http://www.rxlist.com/cgi/generic/loraz.htm
Ativan
fda sheet
Ativan
msds (material safety sheet)
Ativan
Synthesis Reference
Childress, Gluckman, J. Pharm. Sci. 53, 577 (1964)
Ativan
Molecular Weight
321.158 g/mol
Ativan
Melting Point
166-168oC
Ativan
H2O Solubility
0.08 mg/mL
Ativan
State
Solid
Ativan
LogP
2.959
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Dosage Forms
Tablet; Injection
Ativan
Indication
For the management of anxiety disorders or for the short-term relief of the symptoms of anxiety or anxiety associated with depressive symptoms
Ativan
Pharmacology
Lorazepam, a benzodiazepine not transformed to active metabolites, is used to treat anxiety, status epilepticus, and for sedation induction and anterograde amnesia.
Ativan
Absorption
Readily absorbed with an absolute bioavailability of 90%.
Ativan
side effects and Toxicity
Somnolence, confusion, and coma, LD50=3178mg/kg (orally in mice).
Ativan
Patient Information
Lorazepam is a benzodiazepine used for the treatment of anxiety, anxiety with depression, and insomnia. Inform
your physician if you are pregnant or nursing. Lorazepam may cause dizziness and drowsiness; use caution while
driving or operating hazardous machinery. Do not take any other sedating drugs or drink alcohol while taking this
medication. Lorazepam may be habit forming. It is advisable that patients consult with their physician before
changing the dose. Withdrawal symptoms may occur after you stop taking it. This medication may be taken with or
without food.
Ativan
Organisms Affected
Humans and other mammals