Sedazin
Brand names,
Sedazin
Analogs
Sedazin
Brand Names Mixture
Sedazin
Chemical_Formula
C15H10Cl2N2O2
Sedazin
RX_link
http://www.rxlist.com/cgi/generic/loraz.htm
Sedazin
fda sheet
Sedazin
msds (material safety sheet)
Sedazin
Synthesis Reference
Childress, Gluckman, J. Pharm. Sci. 53, 577 (1964)
Sedazin
Molecular Weight
321.158 g/mol
Sedazin
Melting Point
166-168oC
Sedazin
H2O Solubility
0.08 mg/mL
Sedazin
State
Solid
Sedazin
LogP
2.959
Sedazin
Dosage Forms
Tablet; Injection
Sedazin
Indication
For the management of anxiety disorders or for the short-term relief of the symptoms of anxiety or anxiety associated with depressive symptoms
Sedazin
Pharmacology
Lorazepam, a benzodiazepine not transformed to active metabolites, is used to treat anxiety, status epilepticus, and for sedation induction and anterograde amnesia.
Sedazin
Absorption
Readily absorbed with an absolute bioavailability of 90%.
Sedazin
side effects and Toxicity
Somnolence, confusion, and coma, LD50=3178mg/kg (orally in mice).
Sedazin
Patient Information
Lorazepam is a benzodiazepine used for the treatment of anxiety, anxiety with depression, and insomnia. Inform
your physician if you are pregnant or nursing. Lorazepam may cause dizziness and drowsiness; use caution while
driving or operating hazardous machinery. Do not take any other sedating drugs or drink alcohol while taking this
medication. Lorazepam may be habit forming. It is advisable that patients consult with their physician before
changing the dose. Withdrawal symptoms may occur after you stop taking it. This medication may be taken with or
without food.
Sedazin
Organisms Affected
Humans and other mammals