Alzapam
Brand names,
Alzapam
Analogs
Alzapam
Brand Names Mixture
Alzapam
Chemical_Formula
C15H10Cl2N2O2
Alzapam
RX_link
http://www.rxlist.com/cgi/generic/loraz.htm
Alzapam
fda sheet
Alzapam
msds (material safety sheet)
Alzapam
Synthesis Reference
Childress, Gluckman, J. Pharm. Sci. 53, 577 (1964)
Alzapam
Molecular Weight
321.158 g/mol
Alzapam
Melting Point
166-168oC
Alzapam
H2O Solubility
0.08 mg/mL
Alzapam
State
Solid
Alzapam
LogP
2.959
Alzapam
Dosage Forms
Tablet; Injection
Alzapam
Indication
For the management of anxiety disorders or for the short-term relief of the symptoms of anxiety or anxiety associated with depressive symptoms
Alzapam
Pharmacology
Lorazepam, a benzodiazepine not transformed to active metabolites, is used to treat anxiety, status epilepticus, and for sedation induction and anterograde amnesia.
Alzapam
Absorption
Readily absorbed with an absolute bioavailability of 90%.
Alzapam
side effects and Toxicity
Somnolence, confusion, and coma, LD50=3178mg/kg (orally in mice).
Alzapam
Patient Information
Lorazepam is a benzodiazepine used for the treatment of anxiety, anxiety with depression, and insomnia. Inform
your physician if you are pregnant or nursing. Lorazepam may cause dizziness and drowsiness; use caution while
driving or operating hazardous machinery. Do not take any other sedating drugs or drink alcohol while taking this
medication. Lorazepam may be habit forming. It is advisable that patients consult with their physician before
changing the dose. Withdrawal symptoms may occur after you stop taking it. This medication may be taken with or
without food.
Alzapam
Organisms Affected
Humans and other mammals