Loraz
Brand names,
Loraz
Analogs
Loraz
Brand Names Mixture
Loraz
Chemical_Formula
C15H10Cl2N2O2
Loraz
RX_link
http://www.rxlist.com/cgi/generic/loraz.htm
Loraz
fda sheet
Loraz
msds (material safety sheet)
Loraz
Synthesis Reference
Childress, Gluckman, J. Pharm. Sci. 53, 577 (1964)
Loraz
Molecular Weight
321.158 g/mol
Loraz
Melting Point
166-168oC
Loraz
H2O Solubility
0.08 mg/mL
Loraz
State
Solid
Loraz
LogP
2.959
Loraz
Dosage Forms
Tablet; Injection
Loraz
Indication
For the management of anxiety disorders or for the short-term relief of the symptoms of anxiety or anxiety associated with depressive symptoms
Loraz
Pharmacology
Lorazepam, a benzodiazepine not transformed to active metabolites, is used to treat anxiety, status epilepticus, and for sedation induction and anterograde amnesia.
Loraz
Absorption
Readily absorbed with an absolute bioavailability of 90%.
Loraz
side effects and Toxicity
Somnolence, confusion, and coma, LD50=3178mg/kg (orally in mice).
Loraz
Patient Information
Lorazepam is a benzodiazepine used for the treatment of anxiety, anxiety with depression, and insomnia. Inform
your physician if you are pregnant or nursing. Lorazepam may cause dizziness and drowsiness; use caution while
driving or operating hazardous machinery. Do not take any other sedating drugs or drink alcohol while taking this
medication. Lorazepam may be habit forming. It is advisable that patients consult with their physician before
changing the dose. Withdrawal symptoms may occur after you stop taking it. This medication may be taken with or
without food.
Loraz
Organisms Affected
Humans and other mammals