Lorazepam Intensol
Brand names,
Lorazepam Intensol
Analogs
Lorazepam Intensol
Brand Names Mixture
Lorazepam Intensol
Chemical_Formula
C15H10Cl2N2O2
Lorazepam Intensol
RX_link
http://www.rxlist.com/cgi/generic/loraz.htm
Lorazepam Intensol
fda sheet
Lorazepam Intensol
msds (material safety sheet)
Lorazepam Intensol
Synthesis Reference
Childress, Gluckman, J. Pharm. Sci. 53, 577 (1964)
Lorazepam Intensol
Molecular Weight
321.158 g/mol
Lorazepam Intensol
Melting Point
166-168oC
Lorazepam Intensol
H2O Solubility
0.08 mg/mL
Lorazepam Intensol
State
Solid
Lorazepam Intensol
LogP
2.959
Lorazepam Intensol
Dosage Forms
Tablet; Injection
Lorazepam Intensol
Indication
For the management of anxiety disorders or for the short-term relief of the symptoms of anxiety or anxiety associated with depressive symptoms
Lorazepam Intensol
Pharmacology
Lorazepam, a benzodiazepine not transformed to active metabolites, is used to treat anxiety, status epilepticus, and for sedation induction and anterograde amnesia.
Lorazepam Intensol
Absorption
Readily absorbed with an absolute bioavailability of 90%.
Lorazepam Intensol
side effects and Toxicity
Somnolence, confusion, and coma, LD50=3178mg/kg (orally in mice).
Lorazepam Intensol
Patient Information
Lorazepam is a benzodiazepine used for the treatment of anxiety, anxiety with depression, and insomnia. Inform
your physician if you are pregnant or nursing. Lorazepam may cause dizziness and drowsiness; use caution while
driving or operating hazardous machinery. Do not take any other sedating drugs or drink alcohol while taking this
medication. Lorazepam may be habit forming. It is advisable that patients consult with their physician before
changing the dose. Withdrawal symptoms may occur after you stop taking it. This medication may be taken with or
without food.
Lorazepam Intensol
Organisms Affected
Humans and other mammals