Somagerol
Brand names,
Somagerol
Analogs
Somagerol
Brand Names Mixture
Somagerol
Chemical_Formula
C15H10Cl2N2O2
Somagerol
RX_link
http://www.rxlist.com/cgi/generic/loraz.htm
Somagerol
fda sheet
Somagerol
msds (material safety sheet)
Somagerol
Synthesis Reference
Childress, Gluckman, J. Pharm. Sci. 53, 577 (1964)
Somagerol
Molecular Weight
321.158 g/mol
Somagerol
Melting Point
166-168oC
Somagerol
H2O Solubility
0.08 mg/mL
Somagerol
State
Solid
Somagerol
LogP
2.959
Somagerol
Dosage Forms
Tablet; Injection
Somagerol
Indication
For the management of anxiety disorders or for the short-term relief of the symptoms of anxiety or anxiety associated with depressive symptoms
Somagerol
Pharmacology
Lorazepam, a benzodiazepine not transformed to active metabolites, is used to treat anxiety, status epilepticus, and for sedation induction and anterograde amnesia.
Somagerol
Absorption
Readily absorbed with an absolute bioavailability of 90%.
Somagerol
side effects and Toxicity
Somnolence, confusion, and coma, LD50=3178mg/kg (orally in mice).
Somagerol
Patient Information
Lorazepam is a benzodiazepine used for the treatment of anxiety, anxiety with depression, and insomnia. Inform
your physician if you are pregnant or nursing. Lorazepam may cause dizziness and drowsiness; use caution while
driving or operating hazardous machinery. Do not take any other sedating drugs or drink alcohol while taking this
medication. Lorazepam may be habit forming. It is advisable that patients consult with their physician before
changing the dose. Withdrawal symptoms may occur after you stop taking it. This medication may be taken with or
without food.
Somagerol
Organisms Affected
Humans and other mammals