Bonatranquan
Brand names,
Bonatranquan
Analogs
Bonatranquan
Brand Names Mixture
Bonatranquan
Chemical_Formula
C15H10Cl2N2O2
Bonatranquan
RX_link
http://www.rxlist.com/cgi/generic/loraz.htm
Bonatranquan
fda sheet
Bonatranquan
msds (material safety sheet)
Bonatranquan
Synthesis Reference
Childress, Gluckman, J. Pharm. Sci. 53, 577 (1964)
Bonatranquan
Molecular Weight
321.158 g/mol
Bonatranquan
Melting Point
166-168oC
Bonatranquan
H2O Solubility
0.08 mg/mL
Bonatranquan
State
Solid
Bonatranquan
LogP
2.959
Bonatranquan
Dosage Forms
Tablet; Injection
Bonatranquan
Indication
For the management of anxiety disorders or for the short-term relief of the symptoms of anxiety or anxiety associated with depressive symptoms
Bonatranquan
Pharmacology
Lorazepam, a benzodiazepine not transformed to active metabolites, is used to treat anxiety, status epilepticus, and for sedation induction and anterograde amnesia.
Bonatranquan
Absorption
Readily absorbed with an absolute bioavailability of 90%.
Bonatranquan
side effects and Toxicity
Somnolence, confusion, and coma, LD50=3178mg/kg (orally in mice).
Bonatranquan
Patient Information
Lorazepam is a benzodiazepine used for the treatment of anxiety, anxiety with depression, and insomnia. Inform
your physician if you are pregnant or nursing. Lorazepam may cause dizziness and drowsiness; use caution while
driving or operating hazardous machinery. Do not take any other sedating drugs or drink alcohol while taking this
medication. Lorazepam may be habit forming. It is advisable that patients consult with their physician before
changing the dose. Withdrawal symptoms may occur after you stop taking it. This medication may be taken with or
without food.
Bonatranquan
Organisms Affected
Humans and other mammals