O-Chlorooxazepam
Brand names,
O-Chlorooxazepam
Analogs
O-Chlorooxazepam
Brand Names Mixture
O-Chlorooxazepam
Chemical_Formula
C15H10Cl2N2O2
O-Chlorooxazepam
RX_link
http://www.rxlist.com/cgi/generic/loraz.htm
O-Chlorooxazepam
fda sheet
O-Chlorooxazepam
msds (material safety sheet)
O-Chlorooxazepam
Synthesis Reference
Childress, Gluckman, J. Pharm. Sci. 53, 577 (1964)
O-Chlorooxazepam
Molecular Weight
321.158 g/mol
O-Chlorooxazepam
Melting Point
166-168oC
O-Chlorooxazepam
H2O Solubility
0.08 mg/mL
O-Chlorooxazepam
State
Solid
O-Chlorooxazepam
LogP
2.959
O-Chlorooxazepam
Dosage Forms
Tablet; Injection
O-Chlorooxazepam
Indication
For the management of anxiety disorders or for the short-term relief of the symptoms of anxiety or anxiety associated with depressive symptoms
O-Chlorooxazepam
Pharmacology
Lorazepam, a benzodiazepine not transformed to active metabolites, is used to treat anxiety, status epilepticus, and for sedation induction and anterograde amnesia.
O-Chlorooxazepam
Absorption
Readily absorbed with an absolute bioavailability of 90%.
O-Chlorooxazepam
side effects and Toxicity
Somnolence, confusion, and coma, LD50=3178mg/kg (orally in mice).
O-Chlorooxazepam
Patient Information
Lorazepam is a benzodiazepine used for the treatment of anxiety, anxiety with depression, and insomnia. Inform
your physician if you are pregnant or nursing. Lorazepam may cause dizziness and drowsiness; use caution while
driving or operating hazardous machinery. Do not take any other sedating drugs or drink alcohol while taking this
medication. Lorazepam may be habit forming. It is advisable that patients consult with their physician before
changing the dose. Withdrawal symptoms may occur after you stop taking it. This medication may be taken with or
without food.
O-Chlorooxazepam
Organisms Affected
Humans and other mammals