O-Chloroxazepam
Brand names,
O-Chloroxazepam
Analogs
O-Chloroxazepam
Brand Names Mixture
O-Chloroxazepam
Chemical_Formula
C15H10Cl2N2O2
O-Chloroxazepam
RX_link
http://www.rxlist.com/cgi/generic/loraz.htm
O-Chloroxazepam
fda sheet
O-Chloroxazepam
msds (material safety sheet)
O-Chloroxazepam
Synthesis Reference
Childress, Gluckman, J. Pharm. Sci. 53, 577 (1964)
O-Chloroxazepam
Molecular Weight
321.158 g/mol
O-Chloroxazepam
Melting Point
166-168oC
O-Chloroxazepam
H2O Solubility
0.08 mg/mL
O-Chloroxazepam
State
Solid
O-Chloroxazepam
LogP
2.959
O-Chloroxazepam
Dosage Forms
Tablet; Injection
O-Chloroxazepam
Indication
For the management of anxiety disorders or for the short-term relief of the symptoms of anxiety or anxiety associated with depressive symptoms
O-Chloroxazepam
Pharmacology
Lorazepam, a benzodiazepine not transformed to active metabolites, is used to treat anxiety, status epilepticus, and for sedation induction and anterograde amnesia.
O-Chloroxazepam
Absorption
Readily absorbed with an absolute bioavailability of 90%.
O-Chloroxazepam
side effects and Toxicity
Somnolence, confusion, and coma, LD50=3178mg/kg (orally in mice).
O-Chloroxazepam
Patient Information
Lorazepam is a benzodiazepine used for the treatment of anxiety, anxiety with depression, and insomnia. Inform
your physician if you are pregnant or nursing. Lorazepam may cause dizziness and drowsiness; use caution while
driving or operating hazardous machinery. Do not take any other sedating drugs or drink alcohol while taking this
medication. Lorazepam may be habit forming. It is advisable that patients consult with their physician before
changing the dose. Withdrawal symptoms may occur after you stop taking it. This medication may be taken with or
without food.
O-Chloroxazepam
Organisms Affected
Humans and other mammals