PharmacyCodes



Sulfamethizole en es it fr

Sulfamethizole Brand names, Sulfamethizole Analogs

Sulfamethizole Brand Names Mixture

  • No information avaliable

Sulfamethizole Chemical_Formula

C9H10N4O2S2

Sulfamethizole RX_link

No information avaliable

Sulfamethizole fda sheet

Sulfamethizole msds (material safety sheet)

Sulfamethizole Synthesis Reference

No information avaliable

Sulfamethizole Molecular Weight

270.333 g/mol

Sulfamethizole Melting Point

208 oC

Sulfamethizole H2O Solubility

1050 mg/L

Sulfamethizole State

Solid

Sulfamethizole LogP

2.968

Sulfamethizole Dosage Forms

Tablet

Sulfamethizole Indication

For the treatment of urinary tract infection

Sulfamethizole Pharmacology

Sulfamethizole is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.

Sulfamethizole Absorption

Rapidly absorbed.

Sulfamethizole side effects and Toxicity

No information avaliable

Sulfamethizole Patient Information

Sulfamethizole Organisms Affected

Enteric bacteria and other eubacteria