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Rufol Brand names, Rufol Analogs

Rufol Brand Names Mixture

  • No information avaliable

Rufol Chemical_Formula

C9H10N4O2S2

Rufol RX_link

No information avaliable

Rufol fda sheet

Rufol msds (material safety sheet)

Rufol Synthesis Reference

No information avaliable

Rufol Molecular Weight

270.333 g/mol

Rufol Melting Point

208 oC

Rufol H2O Solubility

1050 mg/L

Rufol State

Solid

Rufol LogP

2.968

Rufol Dosage Forms

Tablet

Rufol Indication

For the treatment of urinary tract infection

Rufol Pharmacology

Sulfamethizole is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.

Rufol Absorption

Rapidly absorbed.

Rufol side effects and Toxicity

No information avaliable

Rufol Patient Information

Rufol Organisms Affected

Enteric bacteria and other eubacteria