PharmacyCodes



Sulphamethizole en es it fr

Sulphamethizole Brand names, Sulphamethizole Analogs

Sulphamethizole Brand Names Mixture

  • No information avaliable

Sulphamethizole Chemical_Formula

C9H10N4O2S2

Sulphamethizole RX_link

No information avaliable

Sulphamethizole fda sheet

Sulphamethizole msds (material safety sheet)

Sulphamethizole Synthesis Reference

No information avaliable

Sulphamethizole Molecular Weight

270.333 g/mol

Sulphamethizole Melting Point

208 oC

Sulphamethizole H2O Solubility

1050 mg/L

Sulphamethizole State

Solid

Sulphamethizole LogP

2.968

Sulphamethizole Dosage Forms

Tablet

Sulphamethizole Indication

For the treatment of urinary tract infection

Sulphamethizole Pharmacology

Sulfamethizole is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.

Sulphamethizole Absorption

Rapidly absorbed.

Sulphamethizole side effects and Toxicity

No information avaliable

Sulphamethizole Patient Information

Sulphamethizole Organisms Affected

Enteric bacteria and other eubacteria