SULFAMETHIAZOLE
SULFAMETHIAZOLE Brand names, SULFAMETHIAZOLE Analogs
- Ayerlucil
- Famet
- Lucosil
- Methazol
- Microsul
- Proklar
- Renasul
- Rufol
- SULFAMETHIAZOLE
- Salimol
- Solfametizolo [Dcit]
- Sulamethizole
- Sulfa Gram
- Sulfamethazole
- Sulfamethizol
- Sulfamethizole [Usan:Inn:Jan]
- Sulfamethizolum [Inn-Latin]
- Sulfamethylthiadiazole
- Sulfametizol [Inn-Spanish]
- Sulfapyelon
- Sulfstat
- Sulfurine
- Sulphamethizole
- Sulphamethyltiadiazole
- Tetracid
- Thidicur
- Thiosulfil
- Thiosulfil Forte
- Ultrasul
- Urocydal
- Urodiaton
- Urolucosil
- Urosulfin
- Uroz
SULFAMETHIAZOLE Brand Names Mixture
- No information avaliable
SULFAMETHIAZOLE Chemical_Formula
C9H10N4O2S2
SULFAMETHIAZOLE RX_link
No information avaliable
SULFAMETHIAZOLE fda sheet
SULFAMETHIAZOLE msds (material safety sheet)
SULFAMETHIAZOLE Synthesis Reference
No information avaliable
SULFAMETHIAZOLE Molecular Weight
270.333 g/mol
SULFAMETHIAZOLE Melting Point
208 oC
SULFAMETHIAZOLE H2O Solubility
1050 mg/L
SULFAMETHIAZOLE State
Solid
SULFAMETHIAZOLE LogP
2.968
SULFAMETHIAZOLE Dosage Forms
Tablet
SULFAMETHIAZOLE Indication
For the treatment of urinary tract infection
SULFAMETHIAZOLE Pharmacology
Sulfamethizole is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.
SULFAMETHIAZOLE Absorption
Rapidly absorbed.
SULFAMETHIAZOLE side effects and Toxicity
No information avaliable
SULFAMETHIAZOLE Patient Information
SULFAMETHIAZOLE Organisms Affected
Enteric bacteria and other eubacteria
