Thiosulfil Forte
Brand names,
Thiosulfil Forte
Analogs
Thiosulfil Forte
Brand Names Mixture
Thiosulfil Forte
Chemical_Formula
C9H10N4O2S2
Thiosulfil Forte
RX_link
No information avaliable
Thiosulfil Forte
fda sheet
Thiosulfil Forte
msds (material safety sheet)
Thiosulfil Forte
Synthesis Reference
No information avaliable
Thiosulfil Forte
Molecular Weight
270.333 g/mol
Thiosulfil Forte
Melting Point
208 oC
Thiosulfil Forte
H2O Solubility
1050 mg/L
Thiosulfil Forte
State
Solid
Thiosulfil Forte
LogP
2.968
Thiosulfil Forte
Dosage Forms
Tablet
Thiosulfil Forte
Indication
For the treatment of urinary tract infection
Thiosulfil Forte
Pharmacology
Sulfamethizole is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.
Thiosulfil Forte
Absorption
Rapidly absorbed.
Thiosulfil Forte
side effects and Toxicity
No information avaliable
Thiosulfil Forte
Patient Information
Thiosulfil Forte
Organisms Affected
Enteric bacteria and other eubacteria