Tetracid
Brand names,
Tetracid
Analogs
Tetracid
Brand Names Mixture
Tetracid
Chemical_Formula
C9H10N4O2S2
Tetracid
RX_link
No information avaliable
Tetracid
fda sheet
Tetracid
msds (material safety sheet)
Tetracid
Synthesis Reference
No information avaliable
Tetracid
Molecular Weight
270.333 g/mol
Tetracid
Melting Point
208 oC
Tetracid
H2O Solubility
1050 mg/L
Tetracid
State
Solid
Tetracid
LogP
2.968
Tetracid
Dosage Forms
Tablet
Tetracid
Indication
For the treatment of urinary tract infection
Tetracid
Pharmacology
Sulfamethizole is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.
Tetracid
Absorption
Rapidly absorbed.
Tetracid
side effects and Toxicity
No information avaliable
Tetracid
Patient Information
Tetracid
Organisms Affected
Enteric bacteria and other eubacteria