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Sulfamethazole Brand names, Sulfamethazole Analogs

Sulfamethazole Brand Names Mixture

  • No information avaliable

Sulfamethazole Chemical_Formula

C9H10N4O2S2

Sulfamethazole RX_link

No information avaliable

Sulfamethazole fda sheet

Sulfamethazole msds (material safety sheet)

Sulfamethazole Synthesis Reference

No information avaliable

Sulfamethazole Molecular Weight

270.333 g/mol

Sulfamethazole Melting Point

208 oC

Sulfamethazole H2O Solubility

1050 mg/L

Sulfamethazole State

Solid

Sulfamethazole LogP

2.968

Sulfamethazole Dosage Forms

Tablet

Sulfamethazole Indication

For the treatment of urinary tract infection

Sulfamethazole Pharmacology

Sulfamethizole is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.

Sulfamethazole Absorption

Rapidly absorbed.

Sulfamethazole side effects and Toxicity

No information avaliable

Sulfamethazole Patient Information

Sulfamethazole Organisms Affected

Enteric bacteria and other eubacteria