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Sulfamethizol Brand names, Sulfamethizol Analogs

Sulfamethizol Brand Names Mixture

  • No information avaliable

Sulfamethizol Chemical_Formula

C9H10N4O2S2

Sulfamethizol RX_link

No information avaliable

Sulfamethizol fda sheet

Sulfamethizol msds (material safety sheet)

Sulfamethizol Synthesis Reference

No information avaliable

Sulfamethizol Molecular Weight

270.333 g/mol

Sulfamethizol Melting Point

208 oC

Sulfamethizol H2O Solubility

1050 mg/L

Sulfamethizol State

Solid

Sulfamethizol LogP

2.968

Sulfamethizol Dosage Forms

Tablet

Sulfamethizol Indication

For the treatment of urinary tract infection

Sulfamethizol Pharmacology

Sulfamethizole is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.

Sulfamethizol Absorption

Rapidly absorbed.

Sulfamethizol side effects and Toxicity

No information avaliable

Sulfamethizol Patient Information

Sulfamethizol Organisms Affected

Enteric bacteria and other eubacteria