PharmacyCodes



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Proklar Brand names, Proklar Analogs

Proklar Brand Names Mixture

  • No information avaliable

Proklar Chemical_Formula

C9H10N4O2S2

Proklar RX_link

No information avaliable

Proklar fda sheet

Proklar msds (material safety sheet)

Proklar Synthesis Reference

No information avaliable

Proklar Molecular Weight

270.333 g/mol

Proklar Melting Point

208 oC

Proklar H2O Solubility

1050 mg/L

Proklar State

Solid

Proklar LogP

2.968

Proklar Dosage Forms

Tablet

Proklar Indication

For the treatment of urinary tract infection

Proklar Pharmacology

Sulfamethizole is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.

Proklar Absorption

Rapidly absorbed.

Proklar side effects and Toxicity

No information avaliable

Proklar Patient Information

Proklar Organisms Affected

Enteric bacteria and other eubacteria