Selectin

Selectin Brand names, Selectin Analogs

Selectin Brand Names Mixture

No information avaliable

Selectin Chemical_Formula

C₂₃H₃₆O₇

Selectin RX_link

http://www.rxlist.com/cgi/generic/pravast.htm

Selectin fda sheet

Selectin FDA

Selectin msds (material safety sheet)

Selectin Synthesis Reference

A. Terahara, M.Tanaka, U.S. Pat. 4,346,227(1982)

Selectin Molecular Weight

424.528 g/mol

Selectin Melting Point

326^oC

Selectin H₂O Solubility

2464mg/L

Selectin State

Solid

Selectin LogP

2.613

Selectin Dosage Forms

Tablet

Selectin Indication

For the treatment of hypercholesterolemia to reduce the risk of myocardial infarction.

Selectin Pharmacology

Pravastatin, an antilipemic agent, is used to treat primary hypercholesterolemia. Unlike lovastatin and simvastatin, pravastatin is relatively hydrophilic and does not require hydrolysis for activation.

Selectin Absorption

Average oral absorption of pravastatin is 34% and absolute bioavailability is 17%.

Selectin side effects and Toxicity

Rhabdomyolysis; LD₅₀=mg/kg (orally in rat)

Selectin Patient Information

Patients should be advised to report promptly unexplained muscle pain, tenderness or weakness, particularly if accompanied by malaise or fever.

Selectin Organisms Affected

Humans and other mammals