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Lipostat Brand names, Lipostat Analogs

Lipostat Brand Names Mixture

  • No information avaliable

Lipostat Chemical_Formula

C23H36O7

Lipostat RX_link

http://www.rxlist.com/cgi/generic/pravast.htm

Lipostat fda sheet

Lipostat FDA

Lipostat msds (material safety sheet)

Lipostat Synthesis Reference

A. Terahara, M.Tanaka, U.S. Pat. 4,346,227(1982)

Lipostat Molecular Weight

424.528 g/mol

Lipostat Melting Point

326oC

Lipostat H2O Solubility

2464mg/L

Lipostat State

Solid

Lipostat LogP

2.613

Lipostat Dosage Forms

Tablet

Lipostat Indication

For the treatment of hypercholesterolemia to reduce the risk of myocardial infarction.

Lipostat Pharmacology

Pravastatin, an antilipemic agent, is used to treat primary hypercholesterolemia. Unlike lovastatin and simvastatin, pravastatin is relatively hydrophilic and does not require hydrolysis for activation.

Lipostat Absorption

Average oral absorption of pravastatin is 34% and absolute bioavailability is 17%.

Lipostat side effects and Toxicity

Rhabdomyolysis; LD50=mg/kg (orally in rat)

Lipostat Patient Information

Patients should be advised to report promptly unexplained muscle pain, tenderness or weakness, particularly if accompanied by malaise or fever.

Lipostat Organisms Affected

Humans and other mammals