Lipostat
Lipostat Brand names, Lipostat Analogs
Lipostat Brand Names Mixture
- No information avaliable
Lipostat Chemical_Formula
C23H36O7
Lipostat RX_link
http://www.rxlist.com/cgi/generic/pravast.htm
Lipostat fda sheet
Lipostat msds (material safety sheet)
Lipostat Synthesis Reference
A. Terahara, M.Tanaka, U.S. Pat. 4,346,227(1982)
Lipostat Molecular Weight
424.528 g/mol
Lipostat Melting Point
326oC
Lipostat H2O Solubility
2464mg/L
Lipostat State
Solid
Lipostat LogP
2.613
Lipostat Dosage Forms
Tablet
Lipostat Indication
For the treatment of hypercholesterolemia to reduce the risk of myocardial infarction.
Lipostat Pharmacology
Pravastatin, an antilipemic agent, is used to treat primary hypercholesterolemia. Unlike lovastatin and simvastatin, pravastatin is relatively hydrophilic and does not require hydrolysis for activation.
Lipostat Absorption
Average oral absorption of pravastatin is 34% and absolute bioavailability is 17%.
Lipostat side effects and Toxicity
Rhabdomyolysis; LD50=mg/kg (orally in rat)
Lipostat Patient Information
Patients should be advised to report promptly unexplained muscle pain, tenderness or weakness, particularly if accompanied by malaise or fever.
Lipostat Organisms Affected
Humans and other mammals
