Pravaselect
Pravaselect Brand names, Pravaselect Analogs
Pravaselect Brand Names Mixture
- No information avaliable
Pravaselect Chemical_Formula
C23H36O7
Pravaselect RX_link
http://www.rxlist.com/cgi/generic/pravast.htm
Pravaselect fda sheet
Pravaselect msds (material safety sheet)
Pravaselect Synthesis Reference
A. Terahara, M.Tanaka, U.S. Pat. 4,346,227(1982)
Pravaselect Molecular Weight
424.528 g/mol
Pravaselect Melting Point
326oC
Pravaselect H2O Solubility
2464mg/L
Pravaselect State
Solid
Pravaselect LogP
2.613
Pravaselect Dosage Forms
Tablet
Pravaselect Indication
For the treatment of hypercholesterolemia to reduce the risk of myocardial infarction.
Pravaselect Pharmacology
Pravastatin, an antilipemic agent, is used to treat primary hypercholesterolemia. Unlike lovastatin and simvastatin, pravastatin is relatively hydrophilic and does not require hydrolysis for activation.
Pravaselect Absorption
Average oral absorption of pravastatin is 34% and absolute bioavailability is 17%.
Pravaselect side effects and Toxicity
Rhabdomyolysis; LD50=mg/kg (orally in rat)
Pravaselect Patient Information
Patients should be advised to report promptly unexplained muscle pain, tenderness or weakness, particularly if accompanied by malaise or fever.
Pravaselect Organisms Affected
Humans and other mammals
