Pravastatin Sodium
Pravastatin Sodium Brand names, Pravastatin Sodium Analogs
Pravastatin Sodium Brand Names Mixture
- No information avaliable
Pravastatin Sodium Chemical_Formula
C23H36O7
Pravastatin Sodium RX_link
http://www.rxlist.com/cgi/generic/pravast.htm
Pravastatin Sodium fda sheet
Pravastatin Sodium msds (material safety sheet)
Pravastatin Sodium Synthesis Reference
A. Terahara, M.Tanaka, U.S. Pat. 4,346,227(1982)
Pravastatin Sodium Molecular Weight
424.528 g/mol
Pravastatin Sodium Melting Point
326oC
Pravastatin Sodium H2O Solubility
2464mg/L
Pravastatin Sodium State
Solid
Pravastatin Sodium LogP
2.613
Pravastatin Sodium Dosage Forms
Tablet
Pravastatin Sodium Indication
For the treatment of hypercholesterolemia to reduce the risk of myocardial infarction.
Pravastatin Sodium Pharmacology
Pravastatin, an antilipemic agent, is used to treat primary hypercholesterolemia. Unlike lovastatin and simvastatin, pravastatin is relatively hydrophilic and does not require hydrolysis for activation.
Pravastatin Sodium Absorption
Average oral absorption of pravastatin is 34% and absolute bioavailability is 17%.
Pravastatin Sodium side effects and Toxicity
Rhabdomyolysis; LD50=mg/kg (orally in rat)
Pravastatin Sodium Patient Information
Patients should be advised to report promptly unexplained muscle pain, tenderness or weakness, particularly if accompanied by malaise or fever.
Pravastatin Sodium Organisms Affected
Humans and other mammals
