Pravastatine [French]

Pravastatine [French] Brand names, Pravastatine [French] Analogs

Pravastatine [French] Brand Names Mixture

No information avaliable

Pravastatine [French] Chemical_Formula

C₂₃H₃₆O₇

Pravastatine [French] RX_link

http://www.rxlist.com/cgi/generic/pravast.htm

Pravastatine [French] fda sheet

Pravastatine_[French] FDA

Pravastatine [French] msds (material safety sheet)

Pravastatine [French] Synthesis Reference

A. Terahara, M.Tanaka, U.S. Pat. 4,346,227(1982)

Pravastatine [French] Molecular Weight

424.528 g/mol

Pravastatine [French] Melting Point

326^oC

Pravastatine [French] H₂O Solubility

2464mg/L

Pravastatine [French] State

Solid

Pravastatine [French] LogP

2.613

Pravastatine [French] Dosage Forms

Tablet

Pravastatine [French] Indication

For the treatment of hypercholesterolemia to reduce the risk of myocardial infarction.

Pravastatine [French] Pharmacology

Pravastatin, an antilipemic agent, is used to treat primary hypercholesterolemia. Unlike lovastatin and simvastatin, pravastatin is relatively hydrophilic and does not require hydrolysis for activation.

Pravastatine [French] Absorption

Average oral absorption of pravastatin is 34% and absolute bioavailability is 17%.

Pravastatine [French] side effects and Toxicity

Rhabdomyolysis; LD₅₀=mg/kg (orally in rat)

Pravastatine [French] Patient Information

Patients should be advised to report promptly unexplained muscle pain, tenderness or weakness, particularly if accompanied by malaise or fever.

Pravastatine [French] Organisms Affected

Humans and other mammals