Selipran
Selipran Brand names, Selipran Analogs
Selipran Brand Names Mixture
- No information avaliable
Selipran Chemical_Formula
C23H36O7
Selipran RX_link
http://www.rxlist.com/cgi/generic/pravast.htm
Selipran fda sheet
Selipran msds (material safety sheet)
Selipran Synthesis Reference
A. Terahara, M.Tanaka, U.S. Pat. 4,346,227(1982)
Selipran Molecular Weight
424.528 g/mol
Selipran Melting Point
326oC
Selipran H2O Solubility
2464mg/L
Selipran State
Solid
Selipran LogP
2.613
Selipran Dosage Forms
Tablet
Selipran Indication
For the treatment of hypercholesterolemia to reduce the risk of myocardial infarction.
Selipran Pharmacology
Pravastatin, an antilipemic agent, is used to treat primary hypercholesterolemia. Unlike lovastatin and simvastatin, pravastatin is relatively hydrophilic and does not require hydrolysis for activation.
Selipran Absorption
Average oral absorption of pravastatin is 34% and absolute bioavailability is 17%.
Selipran side effects and Toxicity
Rhabdomyolysis; LD50=mg/kg (orally in rat)
Selipran Patient Information
Patients should be advised to report promptly unexplained muscle pain, tenderness or weakness, particularly if accompanied by malaise or fever.
Selipran Organisms Affected
Humans and other mammals
