Vasten
Vasten Brand names, Vasten Analogs
Vasten Brand Names Mixture
- No information avaliable
Vasten Chemical_Formula
C23H36O7
Vasten RX_link
http://www.rxlist.com/cgi/generic/pravast.htm
Vasten fda sheet
Vasten msds (material safety sheet)
Vasten Synthesis Reference
A. Terahara, M.Tanaka, U.S. Pat. 4,346,227(1982)
Vasten Molecular Weight
424.528 g/mol
Vasten Melting Point
326oC
Vasten H2O Solubility
2464mg/L
Vasten State
Solid
Vasten LogP
2.613
Vasten Dosage Forms
Tablet
Vasten Indication
For the treatment of hypercholesterolemia to reduce the risk of myocardial infarction.
Vasten Pharmacology
Pravastatin, an antilipemic agent, is used to treat primary hypercholesterolemia. Unlike lovastatin and simvastatin, pravastatin is relatively hydrophilic and does not require hydrolysis for activation.
Vasten Absorption
Average oral absorption of pravastatin is 34% and absolute bioavailability is 17%.
Vasten side effects and Toxicity
Rhabdomyolysis; LD50=mg/kg (orally in rat)
Vasten Patient Information
Patients should be advised to report promptly unexplained muscle pain, tenderness or weakness, particularly if accompanied by malaise or fever.
Vasten Organisms Affected
Humans and other mammals
