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Vasten Brand names, Vasten Analogs

Vasten Brand Names Mixture

  • No information avaliable

Vasten Chemical_Formula

C23H36O7

Vasten RX_link

http://www.rxlist.com/cgi/generic/pravast.htm

Vasten fda sheet

Vasten FDA

Vasten msds (material safety sheet)

Vasten Synthesis Reference

A. Terahara, M.Tanaka, U.S. Pat. 4,346,227(1982)

Vasten Molecular Weight

424.528 g/mol

Vasten Melting Point

326oC

Vasten H2O Solubility

2464mg/L

Vasten State

Solid

Vasten LogP

2.613

Vasten Dosage Forms

Tablet

Vasten Indication

For the treatment of hypercholesterolemia to reduce the risk of myocardial infarction.

Vasten Pharmacology

Pravastatin, an antilipemic agent, is used to treat primary hypercholesterolemia. Unlike lovastatin and simvastatin, pravastatin is relatively hydrophilic and does not require hydrolysis for activation.

Vasten Absorption

Average oral absorption of pravastatin is 34% and absolute bioavailability is 17%.

Vasten side effects and Toxicity

Rhabdomyolysis; LD50=mg/kg (orally in rat)

Vasten Patient Information

Patients should be advised to report promptly unexplained muscle pain, tenderness or weakness, particularly if accompanied by malaise or fever.

Vasten Organisms Affected

Humans and other mammals